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Molecular Basis for Inhibition of GH84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion
Author: Marcelo, Filipa, Author: He, Yuan, Author: Yuzwa, Scott A., Author: Nieto, Lidia, Author: Jiménez-Barbero, Jesús, Author: Sollogoub, Matthieu, Author: Vocadlo, David J., Author: Davies, Gideon D., Author: Blériot, Yves
Date created: 2009-03-30
Probing Synergy between Two Catalytic Strategies in the Glycoside Hydrolase O-GlcNAcase Using Multiple Linear Free Energy Relationships
Author: Greig, Ian R., Author: Macauley, Matthew S., Author: Williams, Ian H., Author: Vocadlo, David J.
Date created: 2009-08-28
Visualizing the Reaction Coordinate of an O-GlcNAc Hydrolase
Author: He, Yuan, Author: Macauley, Matthew S., Author: Stubbs, Keith A., Author: Vocadlo, David J., Author: Davies, Gideon J.
Date created: 2010-01-12
Fluorescence-Quenched Substrates for Live Cell Imaging of Human Glucocerebrosidase Activity
Author: Yadav, Anuj K., Author: Shen, David L., Author: Shan, Xiaoyang, Author: He, Xu, Author: Kermode, Allison, Author: Vocadlo, David J.
Date created: 2015-01-05
Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose
Author: Shen, David L., Author: Liu, Ta-Wei, Author: Zandberg, Wesley, Author: Clark, Tom, Author: Eskandari, Razieh, Author: Alteen, Matthew G., Author: Tan, Hong Yee, Author: Zhu, Yanping, Author: Cecioni, Samy, Author: Vocadlo, David
Date created: 2016-12-01
Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates
The full text of this paper will be available in February, 2021 due to the embargo policies of Journal of the ACS Chemical Biology. Contact summit@sfu.ca to enquire if the full text of the accepted manuscript can be made available to you.
Author: Deen, Matthew C., Author: Proceviat, Cameron, Author: Shan, Xiaoyang, Author: Wu, Liang, Author: Shen, David L., Author: Davies, Gideon J., Author: Vocadlo, David J.
Date created: 2020-02-28
Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human O-GlcNAcase:  Mechanistic and Structural Insights into Inhibitor Selectivity and Transition State Poise
Author: Whitworth, Garrett E., Author: Macauley, Matthew S., Author: Stubbs, Keith A., Author: Dennis, Rebecca J., Author: Taylor, Edward J., Author: Davies, Gideon J., Author: Greig, Ian R., Author: Vocadlo, David J.
Date created: 2006-12-23
Identification of Asp174 and Asp175 as the Key Catalytic Residues of Human O-GlcNAcase by Functional Analysis of Site-Directed Mutants
Author: Whitworth, Garrett E., Author: Macauley, Matthew S., Author: Stubbs, Keith A., Author: Dennis, Rebecca J., Author: Taylor, Edward J., Author: Davies, Gideon J., Author: Greig, Ian R., Author: Vocadlo, David J.
Date created: 2006-02-24
Synthesis and Use of Mechanism-Based Protein-Profiling Probes for Retaining β-d-Glucosaminidases Facilitate Identification of Pseudomonas aeruginosa NagZ
Author: Stubbs, Keith A., Author: Scaffidi, Adrian, Author: Debowski, Aleksandra W., Author: Mark, Brian L., Author: Stick, Robert V., Author: Vocadlo, David J.
Date created: 2007-12-08