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Data for Cannabidiol potentiates Hyperpolarization and Cyclic-Nucleotide gated (HCN4) channels

Resource type
Date created
2023-11-03
Authors/Contributors
Author: Page, Dana
Abstract
This data accompanies the work "Cannabidiol potentiates Hyperpolarization and Cyclic-Nucleotide gated (HCN4) channels." published in the Journal of General Physiology. https://doi.org/10.1085/jgp.202313505
Description
The dataset consists of an Excel file containing two sheets. The first sheet is named General Activation Data and the second sheet is named UDI.
"General Activation Data" sheet contains multiple analyses and reports the following types of data from HCN4 channels with a variety of concentrations of CBD, as well as cAMP and diC8-PIP2:
Activation V1/2
Relative Peak Current
Activation Time Constants

"UDI" sheet contains the activation time constants from a 1/3 Hz Use-Dependence protocol before and after treatment with 5 uM CBD

Identifier
DOI: 10.1085/jgp.202313505
Copyright statement
Copyright is held by the author(s).
Scholarly level

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