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Design and synthesis of a photoaffinity labelling analogue of ivacaftor to probe its putative binding site on mutant CFTR
Supplementary file for node/17054 (Full text)

Supplementary file for node/17054 (Full text)

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Design and synthesis of a photoaffinity labelling analogue of ivacaftor to probe its putative binding site on mutant CFTR

Author: Hamilton, Christopher Michael

2017-03-06

The cystic fibrosis (CF) therapeutic, ivacaftor, restores activity to certain cystic fibrosis transmembrane regulating protein (CFTR) mutations;…

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