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Human annotations, especially in highly technical domains, are expensive and time consuming togather, and can also be erroneous. As a result, we never have sufficiently accurate data to train andevaluate supervised methods. In this thesis, we address this problem by taking a semi-supervised approach to biomedical namedentity recognition (NER), and by proposing an inventory-independent evaluation framework for supervised and unsupervised word sense disambiguation. Our contributions are as follows: We introduce a novel graph-based semi-supervised approach to named entity recognition(NER) and exploit pre-trained contextualized word embeddings in several biomedical NER tasks. We propose a new evaluation framework for word sense disambiguation that permits a fair comparison between supervised methods trained on different sense inventories as well as unsupervised methods without a fixed sense inventory.