Skip to main content

Detecting Introgression in Anopheles Mosquito Genomes using a Reconciliation-Based Approach

Resource type
Date created
2018-08-03
Authors/Contributors
Author: Chauve, C.
Author: Feng, J.
Author: Wang, L.
Abstract
Introgression is an important evolutionary mechanism in insects and animals evolution. Current methods for detecting introgression rely on the analysis of phylogenetic incongruence, using either statistical tests based on expected phylogenetic patterns in small phylogenies or probabilistic modeling in a phylogenetic network context. Introgression leaves a phylogenetic signal similar to horizontal gene transfer, and it has been suggested that its detection can also be approached through the gene tree / species tree reconciliation framework, which accounts jointly for other evolutionary mechanisms such as gene duplication and gene loss. However so far the use of a reconciliation-based approach to detect introgression has not been investigated in large datasets. In this work, we apply this principle to a large dataset of Anopheles mosquito genomes. Our reconciliation-based approach recovers the extensive introgression that occurs in the gambiae complex, although with some variations compared to previous reports. Our analysis also suggests a possible ancient introgression event involving the ancestor of An. christyi.
Document
Description
Proceedings of the 16th RECOMB Comparative Genomics Satellite Workshop
Copyright statement
Copyright is held by the author(s).
Scholarly level
Peer reviewed?
No
Language
English
Member of collection
Download file Size
recomb-cg_2018_paper_36.pdf 1.67 MB

Views & downloads - as of June 2023

Views: 0
Downloads: 0