Electrical impedance and diffuse optical spectroscopy for early breast cancer diagnosis

In this thesis, we apply sensor-based tools for investigating breast tissue characteristics to identify anomalies, including cancer. The non-invasive technologies utilized are based on the Electrical Impedance Spectroscopy (EIS) and Diffuse Optical Imaging (DOI). As the accuracy of Clinical Breast Examination (CBE) depends on the physician’s experience, these technologies enhance the diagnostic capabilities by providing additional information. We tested twenty patients utilizing these technologies, in a clinical trial, with around 100% success rate in identifying the location of cancerous tumors.The correlation between healthy and cancerous tissue electrical properties is defined by extracting the electrical features of tissues based on Cole-Cole model. Also, by processing the raw data of the DOI-probe, we have been able to create the cross-sectional optical images of the breast in different wavelengths from 690nm to 850nm. This study suggests that EIS and DOI are useful technologies for early detection of breast cancers.