In this research work, systolic time intervals and stroke volume were extracted through the processing of recorded mechanical cardiac vibrations from the sternum, seismocardiogram (SCG). These hemodynamic parameters were extracted based on the physiological characterization of SCG with different modalities including echocardiography, ballistocardiography, Doppler ultrasound, and finite element modelling. For the first time, an extensive evaluation of the SCG estimation of systolic time intervals compared to those from Doppler ultrasound and impedance cardiogram was performed (n=25). It was shown that SCG can estimate pre-ejection period (p-value=0.16), left ventricular ejection time (p-value=0.93), and QS2 (p-value=0.91). In a novel approach, the effects of respiration on SCG was studied on 45 participants. As the results of this study it was found that there is a difference between SCG cycles during inspiration and the ones during expiration (p-value
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Thesis advisor: Kaminska, Bozena
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