Skip to main content

In search of reason: prevention of mother-to-child transmission (PMTCT) failures in the era of programmatic scale-up in Soweto, South Africa

Date created
The 2008 scale-up of South African public sector prevention of mother-to-child transmission (PMTCT) to an AZT/sdNVP regimen led to significant reductions in vertical HIV transmission, yet incident paediatric infections continue. The objectives of this study were to 1) identify mothers of newly HIV-infected infants, and assess whether they received per-guideline PMTCT antiretroviral (ARV) regimens, and 2) qualitatively explore contextual factors contributing to these prescription failures and MTCT risk. Eligible women included birthmothers of HIV-infected infants in Soweto. Participants (n=45) first completed a questionnaire, and then a focus group or structured interview. Through triangulation of data, it was determined that 29 mother-infant pairs (64%) did not receive per-guideline PMTCT ARV regimens. Identified issues of importance include preterm birth, delayed antenatal care attendance, operational difficulties implementing PMTCT, and HIV-related stigma. While improved PMTCT regimens are available, social and structural factors must be addressed to ensure access to and uptake of prevention services.
Copyright statement
Copyright is held by the author.
The author granted permission for the file to be printed and for the text to be copied and pasted.
Scholarly level
Member of collection
Download file Size
etd6332_ACescon.pdf 1.09 MB

Views & downloads - as of June 2023

Views: 0
Downloads: 0