Fixed Drug Eruption Resulting from Fluconazole Use: A Case Report

Introduction: Fluconazole is a widely used antifungal agent with a possible side effect of fixed drugeruption. However, this adverse drug effect is absent from the reported list of possible side effects offluconazole. We are presenting a rare case in our report.Case presentation: A 25-year-old Iranian woman developed fixed drug eruptions on different sitesof her body after taking five doses of fluconazole to treat vaginal candidiasis. A positive patch test,positive oral challenge test and skin biopsy were all found to be consistent with fixed drug eruption.Conclusion: Fluconazole is a widely prescribed drug, used mainly to treat candidiasis. Fixed drugeruption as a possible side effect of Fluconazole is not well known and thus, the lesions may bemisdiagnosed and mistreated. Based on our findings, which are consistent with a number of otherpractitioners, we recommend adding fixed drug eruption to the list of possible side effects offluconazole.