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GExplore: a Web Server for Integrated Queries of Protein Domains, Gene Expression and Mutant Phenotypes

Resource type
Date created
2009
Authors/Contributors
Author: Ng, Man-Ping
Abstract
Background: The majority of the genes even in well-studied multi-cellular model organisms havenot been functionally characterized yet. Mining the numerous genome wide data sets related toprotein function to retrieve potential candidate genes for a particular biological process remains achallenge.Description: GExplore has been developed to provide a user-friendly database interface for datamining at the gene expression/protein function level to help in hypothesis development andexperiment design. It supports combinatorial searches for proteins with certain domains, tissue- ordevelopmental stage-specific expression patterns, and mutant phenotypes. GExplore operates ona stand-alone database and has fast response times, which is essential for exploratory searches. Theinterface is not only user-friendly, but also modular so that it accommodates additional data sets inthe future.Conclusion: GExplore is an online database for quick mining of data related to gene and proteinfunction, providing a multi-gene display of data sets related to the domain composition of proteinsas well as expression and phenotype data. GExplore is publicly available at: http://genome.sfu.ca/gexplore/
Document
Published as
BMC Genomics 2009, 10:529 doi:10.1186/1471-2164-10-529
Publication title
BMC Genomics
Document title
GExplore: a Web Server for Integrated Queries of Protein Domains, Gene Expression and Mutant Phenotypes
Date
2009
Volume
10
Issue
529
Publisher DOI
10.1186/1471-2164-10-529
Copyright statement
Copyright is held by the author(s).
Scholarly level
Peer reviewed?
Yes
Language
English
Member of collection
Download file Size
1471-2164-10-529.pdf 813.65 KB

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