Preparation and covalent surface modifications of silica coated spherical and rod-shaped gold nanoparticles

Author: 
Date created: 
2018-08-17
Identifier: 
etd19826
Keywords: 
Gold nanoparticles
Silica nanoparticles
Surface modification
Alcohols
Microwave
Abstract: 

The surface chemistry of silica-coated gold nanoparticles (Au NPs) was investigated by modifying these surfaces using alcohol-based reagents. Alcohol condensation reactions were facilitated by dielectric heating using a microwave reactor. The attachment of two alcohol-based reagents, a carboxylic acid functionalized alcohol and a chelating agent with a terminal alcohol functional group, was achieved on the surfaces of spherical gold nanoparticles and gold nanorods, respectively. A fluorescent probe was coupled to the carboxylic acid functionalized silica-coated Au NPs as a confirmation of the surface functionalization, and as a demonstration of an application for these nanoparticles. The silica-coated gold nanorods modified with a chelating species were evaluated for their ability to capture metal ions present in an aqueous solution. A wide range of surface chemistry for silica-based nanoparticles can be achieved using the methods presented herein to meet the requirements of their future applications.

Document type: 
Thesis
Rights: 
This thesis may be printed or downloaded for non-commercial research and scholarly purposes. Copyright remains with the author.
File(s): 
Supervisor(s): 
Byron Gates
Department: 
Science: Department of Chemistry
Thesis type: 
(Thesis) M.Sc.
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