Quantitative measurements of biological/chemical concentrations using smartphone cameras

Author: 
Date created: 
2018-11-16
Identifier: 
etd19947
Keywords: 
Smartphone
Image database
Image processing
Color
Fluorescence
Scattering
Abstract: 

This thesis presents a smartphone-based imaging system capable of quantifying the concentration of an assortment of biological/chemical assay samples. The main goal of this thesis work is to construct an image database which characterizes the relationship between color information and concentrations of the biological/chemical assay sample. For this aim, a designated optical setup combined with image processing and data analyzing techniques was implemented. A series of experiments conducted on selected assays, including fluorescein, RNA Mango, homogenized milk and yeast have demonstrated that our proposed system estimates the concentration of fluorescent materials and colloidal mixtures comparable to currently used commercial and laboratory instruments. Furthermore, by utilizing the camera and computational power of smartphones, eventual development can be directed toward extremely compact, inexpensive and portable analysis and diagnostic systems which will allow experiments and tests to be conducted in remote or impoverished areas.

Document type: 
Thesis
Rights: 
This thesis may be printed or downloaded for non-commercial research and scholarly purposes. Copyright remains with the author.
File(s): 
Supervisor(s): 
Ash Parameswaran
Pablo Nepomnaschy
Department: 
Applied Sciences: School of Engineering Science
Thesis type: 
(Thesis) Ph.D.
Statistics: