Visible light wavefront sensorless adaptive optics optical coherence tomography

Author: 
Date created: 
2018-01-11
Identifier: 
etd10541
Keywords: 
Adaptive optics
Wavefront sensorless
Optical coherence tomography
Confocal scanning laser ophthalmoscopy
Mouse retina
Abstract: 

Optical Coherence Tomography (OCT) imaging has predominantly been performed using wavelengths in the near-infrared, however visible light (Vis) has been recently demonstrated, showing encouraging results for high quality retinal imaging. Using a broadband supercontinuum visible light source, a sensorless adaptive optics (SAO) multi-modal imaging system is presented driven by Vis-OCT for volumetric structural imaging, followed by acquisition of fluorescence emission from the sample. The coherence-gated, depth resolved Vis-OCT images can be used for image-guided SAO aberration correction when the fluorescent signal is too weak, providing structural and functional images with high resolution.

Document type: 
Thesis
Rights: 
This thesis may be printed or downloaded for non-commercial research and scholarly purposes. Copyright remains with the author.
File(s): 
Supervisor(s): 
Marinko Sarunic
Department: 
Applied Sciences: School of Engineering Science
Thesis type: 
(Thesis) M.A.Sc.
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