Chemistry - Theses, Dissertations, and other Required Graduate Degree Essays

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Dynamic structure of cholesteryl esters in membranes

Author: 
Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1981
Document type: 
Thesis
File(s): 
Senior supervisor: 
R.J. Cushley
Department: 
Science: Department of Chemistry
Thesis type: 
(Dissertation) Ph.D.

Synthesis of inhibitors of 2,3-oxidosqualene-lanosterol cyclase

Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1992
Document type: 
Thesis
File(s): 
Senior supervisor: 
A.C. Oehlschlager
Department: 
Science: Department of Chemistry
Thesis type: 
(Dissertation) Ph.D.

Magnetic resonance and infra-red studies of insulin and its interaction with phospholipid

Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1992
Document type: 
Thesis
File(s): 
Senior supervisor: 
R.J. Cushley
Department: 
Science: Department of Chemistry
Thesis type: 
(Thesis) M.Sc.

Mechanistic study on the irradiation of iminophosphoranes

Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1977
Document type: 
Thesis
File(s): 
Senior supervisor: 
A.C. Oehlschlager
Department: 
Science: Department of Chemistry
Thesis type: 
Thesis (M.Sc.)

Fabrication and application of semi-conductor radiation detectors in high resolution nuclear decay studies.

Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1967
Abstract: 

Factors which determine performance of lithium-drifted semiconductor radiation detectors, particularly lithium-drifted germanium detectors for gamma-ray spectroscopy, are discussed in terms of general semiconductor theory The analysis includes the effects of electronic noise and the statistical effects of radiation-induced ionization and charge collection in semiconductors. The fabrication technique is discussed for obtaining small volume planar Ge(Li) detectors and large volume (totally compensated) Ge(Li) detectors using the lithium-ion drifting process. In the case of detectors of the former type, devices have been fabricated with unusual operating characteristics; excellent resolution has been obtained from such devices at collection fields as low as 15 volts/mm. A new technique for treating the exposed surfaces of Ge(Li) detectors by coating them with a layer of CaFo which both lowers detector leakage current and protects the surface from exposure to the ambient is discussed. An estimate of the Fano factor in germanium has been made using Ge(Li) detectors. The value of F =0.11 +0.05 has been obtained, and this result as well as previous ones is discussed in terms of the charge collection efficiency of Ge(Li) detectors, the interaction of gamma-rays with matter and the radiation-induced ionization process, and recent theoretical predictions for the Fano factor. The calibration and use of Ge(Li) detectors for gamma-ray spectroscopy is discussed. Detectors fabricated in this laboratory have been used as gamma-ray spectrometers in high resolution nuclear decay studies. In the study of the decay of Co and Mn two previously unobserved gamma-rays have been detected at energies of 3119 3 keV and 3SQ8.7 koV; ?? ? these new transitions result in placing of two levels in Fe at energies of 3119.3 keV and 4445.3 keV which have been previously observed only in nuclear reaction studies. The present study, which has included both single Ge(Li) detector measurements and two-parameter coincidence experiments using a Ge(Li) detector and Nal(Tl) detector, has confirmed c-fl the existence of certain other energy levels in Fe and has provided added information on spin and parity assignments to the levels. The nuclear decay study of Ge has yielded new results for the levels in Ga . A gamma-ray of energy 536.9 keV has been detected for the first time resulting in the placement of a new energy level in Ga of this energy. The previously reported gamma-ray of energy 185 ke V has been resolved with Ge(Li) detectors into two transitions of energies 181.9 keV and 189.8 keV. The existence of a gamma-ray of energy 515.0 keV has been postulated; more precise values for the energies of the other gamma -rays from the decay of Ge have been obtained and a revised decayed scheme has been constructed. Aft The decay of Ga has been studied using Ge(Li) detectors and preliminary gamma-ray data obtained.

Document type: 
Thesis
File(s): 
Senior supervisor: 
B.D. Pate
Department: 
Science: Chemistry Department
Thesis type: 
(Dissertation) Ph.D.

Photolyses of N-nitrosamides in acidic and neutral media.

Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1967
Abstract: 

Photolyses of several N-nitrosamides in acidic and neutral media were studied. The photochemical decomposition of II-nitrosanides was found to involve exclusively nitrogen-nitrogen bond cleavage of the IT-nitrosamide group in contrast to the pyrolytic decomposition which involved cleavage of the acyl nitrogen bond. In acidic media, photolyses of rl-nitrosamides led to the light catalyzed denitrosation of the N-nitrosamides by photo-elimination of the [WOH] group with the formation of alkylidenimides. The alkylidenimides underwent secondary reactions to give the corresponding aldehydes. The photo-elimination products were identified as the 2 ,4-dinitrophenyl-hydrazones of the aldehydes. In neutral media, the primary photolytic process of H-nitrosa.nides was the .formation of nitroso and amide radicals. The amide radical v/as found to abstract intramolecularly a $ hydrogen atom attached to the carbon atom in the S-position^ to give a S-carbon radical. This S-carbon radical then coupled with the nitroso radical to give a C-nitroso compound which either tautomerized to form oxime or dimerized. Alternatively the amide radical underwent elimination of an alpha hydrogen to give the alkylidenimide as an intermediate. if The S-position was numbered in reference to the nitrogen atom of the amide group. For examole , the for vula of & -nitroso-n-hexylformamide would be N=0 0 Ill

Document type: 
Thesis
File(s): 
Senior supervisor: 
Name is illegible
Department: 
Science: Chemistry Department
Thesis type: 
(Thesis) M.Sc.

The formation and decay of the compound mucleur Ge 68.

Peer reviewed: 
No, item is not peer reviewed.
Date created: 
1968
Abstract: 

Experimental excitation functions have been measured by radiochemical means for a number of reactions proceeding through the compound nucleus Ge . The target- li 54 TO ^f, 16 52 projectile pairs were: He +Zn , C +Fe , and 0 +Cr leading to the following reactions: (OO,Y), (x,p), (x,n), (x,pn), and (x,2n). Recoil ranges were measured for products of the alpha-induced reactions in order to determine those reactions which proceeded by compound nucleus formation and decay. It has been found that the "independence hypothesis" is verified for reactions induced by different target-projectile pairs but proceeding through compound nuclei of nearly equal angular momentum. Excitation functions have been calculated with the SFU IBM System. ^60/40 computer via the statistical theory of nuclear reactions according to a formalism containing the explicit dependence of nuclear emission probabilities on angular momentum. Probabilities for Y-ray emission were calculated according to the single-particle model coupled with enhancement functions chosen to reflect experimentally observed collective effects. Agreement between experiment and calculations 64 4 was found to be good for the Zn +He excitation functions. The "high energy tails" of the excitation functions were found to be accounted for by effects of y-ray competition with particle emission when the latter was surpressed by angular momentum effects. Agreement in the Fe +C case was found to be very encouraging, considering the complexity of the target-projectile system and attendant theoretical difficulties.

Document type: 
Thesis
File(s): 
Senior supervisor: 
B.D. Pate
Department: 
Science: Chemistry Department
Thesis type: 
(Dissertation) Ph.D.